Echodide
Brand names,
Echodide
Analogs
Echodide
Brand Names Mixture
Echodide
Chemical_Formula
C15H17FN4O3
Echodide
RX_link
http://www.rxlist.com/cgi/generic2/enoxacin.htm
Echodide
fda sheet
Echodide
msds (material safety sheet)
Echodide
Synthesis Reference
No information avaliable
Echodide
Molecular Weight
320.319 g/mol
Echodide
Melting Point
220-224 oC
Echodide
H2O Solubility
3.43 g/L
Echodide
State
Solid
Echodide
LogP
0.387
Echodide
Dosage Forms
200 mg and 400 mg film-coated tablets
Echodide
Indication
For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria gonorrhoeae, (2) uncomplicated urinary tract infections (cystitis) due to Escherichia coli, Staphylococcus epidermidis, or Staphylococcus saprophyticus, and (3) complicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus epidermidis, or Enterobacter cloacae.
Echodide
Pharmacology
Enoxacin is a quinolone/fluoroquinolone antibiotic. Enoxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Enoxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Enoxacin may be active against pathogens resistant to drugs that act by different mechanisms.
Echodide
Absorption
Rapidly absorbed following oral administration, with an absolute oral bioavailability of approximately 90%.
Echodide
side effects and Toxicity
No information avaliable
Echodide
Patient Information
Echodide
Organisms Affected
Enteric bacteria and other eubacteria