Dobutamine
Brand names,
Dobutamine
Analogs
Dobutamine
Brand Names Mixture
Dobutamine
Chemical_Formula
C18H23NO3
Dobutamine
RX_link
http://www.rxlist.com/cgi/generic3/dobutamine.htm
Dobutamine
fda sheet
Dobutamine
msds (material safety sheet)
Dobutamine
Synthesis Reference
No information avaliable
Dobutamine
Molecular Weight
301.38 g/mol
Dobutamine
Melting Point
No information avaliable
Dobutamine
H2O Solubility
No information avaliable
Dobutamine
State
Solid
Dobutamine
LogP
3.489
Dobutamine
Dosage Forms
Liquid
Dobutamine
Indication
For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures
Dobutamine
Pharmacology
Dobutamine is a direct-acting inotropic agent whose primary activity results from stimulation of the beta-adrenoceptors of the heart while producing comparatively mild chronotropic, hypertensive, arrhythmogenic, and vasodilative effects. Dobutamine acts primarily on beta-1 adrenergic receptors, with little effect on beta-2 or alpha receptors. It does not cause the release of endogenous norepinephrine, as does dopamine. Dobutamine is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
Dobutamine
Absorption
No information avaliable
Dobutamine
side effects and Toxicity
No information avaliable
Dobutamine
Patient Information
No information avaliable
Dobutamine
Organisms Affected
Humans and other mammals