Dobutrex
Brand names,
Dobutrex
Analogs
Dobutrex
Brand Names Mixture
Dobutrex
Chemical_Formula
C18H23NO3
Dobutrex
RX_link
http://www.rxlist.com/cgi/generic3/dobutamine.htm
Dobutrex
fda sheet
Dobutrex
msds (material safety sheet)
Dobutrex
Synthesis Reference
No information avaliable
Dobutrex
Molecular Weight
301.38 g/mol
Dobutrex
Melting Point
No information avaliable
Dobutrex
H2O Solubility
No information avaliable
Dobutrex
State
Solid
Dobutrex
LogP
3.489
Dobutrex
Dosage Forms
Liquid
Dobutrex
Indication
For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures
Dobutrex
Pharmacology
Dobutamine is a direct-acting inotropic agent whose primary activity results from stimulation of the beta-adrenoceptors of the heart while producing comparatively mild chronotropic, hypertensive, arrhythmogenic, and vasodilative effects. Dobutamine acts primarily on beta-1 adrenergic receptors, with little effect on beta-2 or alpha receptors. It does not cause the release of endogenous norepinephrine, as does dopamine. Dobutamine is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
Dobutrex
Absorption
No information avaliable
Dobutrex
side effects and Toxicity
No information avaliable
Dobutrex
Patient Information
No information avaliable
Dobutrex
Organisms Affected
Humans and other mammals