Difenidol hydrochloride
Difenidol hydrochloride Brand names, Difenidol hydrochloride Analogs
Difenidol hydrochloride Brand Names Mixture
- No information avaliable
Difenidol hydrochloride Chemical_Formula
C18H27NO2
Difenidol hydrochloride RX_link
No information avaliable
Difenidol hydrochloride fda sheet
Difenidol hydrochloride msds (material safety sheet)
Difenidol hydrochloride Synthesis Reference
No information avaliable
Difenidol hydrochloride Molecular Weight
289.413 g/mol
Difenidol hydrochloride Melting Point
No information avaliable
Difenidol hydrochloride H2O Solubility
Soluble (HCl salt)
Difenidol hydrochloride State
Solid
Difenidol hydrochloride LogP
3.931
Difenidol hydrochloride Dosage Forms
Aerosol (with propellants); Lozenge; Spray; Topical solution
Difenidol hydrochloride Indication
Used to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the esophagus, larynx, mouth, pharynx or throat, respiratory tract or trachea, urinary tract, or vagina. Also used to suppress the gag reflex and/or other laryngeal and esophageal reflexes to facilitate dental examination or procedures (including oral surgery), endoscopy, or intubation. Also used for relief of canker sores, cold sores or fever blister.
Difenidol hydrochloride Pharmacology
Dyclonine is an oral anasthetic. If substantial quantities of local anesthetics are absorbed through the mucosa, actions on the central nervous system (CNS) may cause CNS stimulation and/or CNS depression. Actions on the cardiovascular system may cause depression of cardiac conduction and excitability and, with some of these agents, peripheral vasodilation.
Difenidol hydrochloride Absorption
Readily absorbed through mucous membranes into the systemic circulation. The rate of absorption is influenced by the vascularity or rate of blood flow at the site of application, the total dosage (concentration and volume) administered, and the duration of exposure. Absorption from mucous membranes of the throat or respiratory tract may be especially rapid.
Difenidol hydrochloride side effects and Toxicity
Symptoms of overdose include cardiovascular system depression, CNS toxicity, and methemoglobinemia.
Difenidol hydrochloride Patient Information
No information avaliable
Difenidol hydrochloride Organisms Affected
Humans and other mammals
