Difenidol
Difenidol Brand names, Difenidol Analogs
Difenidol Brand Names Mixture
- No information avaliable
Difenidol Chemical_Formula
C18H27NO2
Difenidol RX_link
No information avaliable
Difenidol fda sheet
Difenidol msds (material safety sheet)
Difenidol Synthesis Reference
No information avaliable
Difenidol Molecular Weight
289.413 g/mol
Difenidol Melting Point
No information avaliable
Difenidol H2O Solubility
Soluble (HCl salt)
Difenidol State
Solid
Difenidol LogP
3.931
Difenidol Dosage Forms
Aerosol (with propellants); Lozenge; Spray; Topical solution
Difenidol Indication
Used to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the esophagus, larynx, mouth, pharynx or throat, respiratory tract or trachea, urinary tract, or vagina. Also used to suppress the gag reflex and/or other laryngeal and esophageal reflexes to facilitate dental examination or procedures (including oral surgery), endoscopy, or intubation. Also used for relief of canker sores, cold sores or fever blister.
Difenidol Pharmacology
Dyclonine is an oral anasthetic. If substantial quantities of local anesthetics are absorbed through the mucosa, actions on the central nervous system (CNS) may cause CNS stimulation and/or CNS depression. Actions on the cardiovascular system may cause depression of cardiac conduction and excitability and, with some of these agents, peripheral vasodilation.
Difenidol Absorption
Readily absorbed through mucous membranes into the systemic circulation. The rate of absorption is influenced by the vascularity or rate of blood flow at the site of application, the total dosage (concentration and volume) administered, and the duration of exposure. Absorption from mucous membranes of the throat or respiratory tract may be especially rapid.
Difenidol side effects and Toxicity
Symptoms of overdose include cardiovascular system depression, CNS toxicity, and methemoglobinemia.
Difenidol Patient Information
No information avaliable
Difenidol Organisms Affected
Humans and other mammals
