Dicloxacycline
Brand names,
Dicloxacycline
Analogs
Dicloxacycline
Brand Names Mixture
- Anaprime OPH Gel (Flumethasone + Neomycin sulfate + Polymyxin B sulfate)
- Antibiotic Cream (Gramicidin + Polymyxin B sulfate)
- Antibiotic Lozenges (Benzocaine + Cetylpyridinium Chloride + Polymyxin B sulfate + Tyrothricin)
- Antibiotic Ointment (Bacitracin + Polymyxin B sulfate)
- Bacitracin-Neomycin Polymyxin Ont (Bacitracin Zinc + Neomycin sulfate + Polymyxin B sulfate)
- Bacitracin-Neomycin-Polymyxin Oph Ont (Bacitracin Zinc + Neomycin sulfate + Polymyxin B sulfate)
- Band-Aid Brand Antibiotic (Bacitracin Zinc + Polymyxin B sulfate)
- Band-Aid-S-1 (Bacitracin Zinc + Polymyxin B sulfate)
- Cortisporin (Bacitracin Zinc + Hydrocortisone + Neomycin sulfate + Polymyxin B sulfate)
- First Aid Antibiotic (Bacitracin Zinc + Polymyxin B sulfate)
- First Aid Antibiotic Ointment (Bacitracin Zinc + Polymyxin B sulfate)
- Forte Topical Suspension (Hydrocortisone Acetate + Hydrocortisone Sodium Succinate + Neomycin sulfate + Penicillin G Procaine + Polymyxin B sulfate)
- Gercillin (Bacitracin + Benzocaine + Polymyxin B sulfate + Tyrothricin)
- Lanabiotic Ont (Bacitracin + Polymyxin B sulfate)
- Laryngets Loz (Benzocaine + Cetylpyridinium Chloride + Polymyxin B sulfate + Tyrothricin)
- Lidomyxin (Lidocaine Hydrochloride + Polymyxin B sulfate)
- Lidosporin Cream (Gramicidin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Lidosporin Ear Drops (Lidocaine Hydrochloride + Polymyxin B sulfate)
- Mastitis Care (Neomycin sulfate + Penicillin G Potassium + Polymyxin B sulfate + Streptomycin sulfate)
- Mycitracin OPH ONT (Bacitracin + Neomycin sulfate + Polymyxin B sulfate)
- Neo Bace Ophthalmic Ointment (Bacitracin + Polymyxin B sulfate)
- Neospan Mastitis Treatment (Neomycin sulfate + Penicillin G Potassium + Polymyxin B sulfate + Streptomycin sulfate)
- Neosporin Antibiotic Cream (Gramicidin + Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Eye-Ear Solution (Gramicidin + Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Irrigating Solution (Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Ointment (Bacitracin (Bacitracin Zinc) + Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Neomycin sulfate + Polymyxin B sulfate)
- Neotopic Ointment (Bacitracin (Bacitracin Zinc) + Neomycin sulfate + Polymyxin B sulfate)
- Ophthocort Ont (Chloramphenicol + Hydrocortisone Acetate + Polymyxin B sulfate)
- Optiprime Oph Gel (Neomycin sulfate + Polymyxin B sulfate)
- Ozonol Antibiotic Plus - Ointment (Bacitracin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Ozonol Antibiotic Plus Ont (Bacitracin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Pms-Polytrimethoprim (Polymyxin B sulfate + Trimethoprim (Trimethoprim sulfate))
- Polycidin Eye, Ear Drops (Gramicidin + Polymyxin B sulfate)
- Polycidin Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Polymyxin B sulfate)
- Polyderm Antibiotic Ointment (Bacitracin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Polyderm Ointment Usp (Bacitracin Zinc + Polymyxin B sulfate)
- Polysporin Antibiotic Burn Cream (Gramicidin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Polysporin Antibiotic Ointment (Bacitracin + Polymyxin B sulfate)
- Polysporin Burn Formula Cream (Gramicidin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Polysporin Cream (Gramicidin + Polymyxin B sulfate)
- Polysporin Eye and Ear Drops Sterile (Gramicidin + Polymyxin B sulfate)
- Polysporin Sterile Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Polymyxin B sulfate)
- Polysporin Topical First Aid Antibiotic Ointment (Bacitracin + Polymyxin B sulfate)
- Polysporin Triple Antibiotic Ointment (Bacitracin + Gramicidin + Polymyxin B sulfate)
- Polytopic Ont (Bacitracin + Polymyxin B sulfate)
- Polytracin Ont (Bacitracin Zinc + Polymyxin B sulfate)
- Pulmosirum Pastille (Benzocaine + Cetylpyridinium Chloride + Polymyxin B sulfate + Tyrothricin)
- Sandoz Cortimyxin (Bacitracin (Bacitracin Zinc) + Hydrocortisone + Neomycin sulfate + Polymyxin B sulfate)
- Septomixine Forte (Dexamethasone + Halethazole Tartrate + Neomycin sulfate + Polymyxin B sulfate + Tyrothricin)
- Surolan Drops (Miconazole Nitrate + Polymyxin B sulfate + Prednisolone Acetate)
- Synalar Bi-Otic Solution (Fluocinolone Acetonide + Neomycin sulfate + Polymyxin B sulfate)
Dicloxacycline
Chemical_Formula
C19H17Cl2N3O5S
Dicloxacycline
RX_link
http://www.rxlist.com/cgi/generic2/diclox.htm
Dicloxacycline
fda sheet
Dicloxacycline
msds (material safety sheet)
Dicloxacycline
Synthesis Reference
No information avaliable
Dicloxacycline
Molecular Weight
470.327 g/mol
Dicloxacycline
Melting Point
No information avaliable
Dicloxacycline
H2O Solubility
3.63 mg/L
Dicloxacycline
State
Solid
Dicloxacycline
LogP
2.893
Dicloxacycline
Dosage Forms
Oral via capsule form or powder for reconstitution.
Dicloxacycline
Indication
Used to treat infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug.
Dicloxacycline
Pharmacology
Dicloxacillin is a beta-lactamase resistant penicillin similar to oxacillin. Dicloxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of dicloxacillin results from the inhibition of cell wall synthesis and is mediated through dicloxacillin binding to penicillin binding proteins (PBPs). Dicloxacillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Dicloxacycline
Absorption
Absorption of the isoxazolyl penicillins after oral administration is rapid but incomplete: peak blood levels are achieved in 1-1.5 hours. Oral absorption of cloxacillin, dicloxacillin, oxacillin and nafcillin is delayed when the drugs are administered after meals.
Dicloxacycline
side effects and Toxicity
Oral LD50 in rat is 3579 mg/kg. Symptoms of overexposure include irritation, rash, labored breathing, hives, itching, wheezing, nausea, chills, and fever.
Dicloxacycline
Patient Information
No information avaliable
Dicloxacycline
Organisms Affected
Enteric bacteria and other eubacteria