Diambutol
Brand names,
Diambutol
Analogs
Diambutol
Brand Names Mixture
Diambutol
Chemical_Formula
C11H12N2O2
Diambutol
RX_link
http://www.rxlist.com/cgi/generic3/peganone.htm
Diambutol
fda sheet
Diambutol
msds (material safety sheet)
Diambutol
Synthesis Reference
No information avaliable
Diambutol
Molecular Weight
204.225 g/mol
Diambutol
Melting Point
94 oC
Diambutol
H2O Solubility
5280 mg/L
Diambutol
State
Solid
Diambutol
LogP
1.083
Diambutol
Dosage Forms
Tablet (250, 500 mg)
Diambutol
Indication
For the control of tonic-clonic (grand mal) and complex partial (psychomotor) seizures.
Diambutol
Pharmacology
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread of seizure activity rather than to abolish the primary focus of seizure discharges.
Diambutol
Absorption
Fairly rapidly absorbed, however, the extent of oral absorption is not known.
Diambutol
side effects and Toxicity
Symptoms of overdose include drowsiness, loss of or impaired muscle coordination, nausea, visual disturbance, and, at very high doses, coma.
Diambutol
Patient Information
Diambutol
Organisms Affected
Humans and other mammals