Dapiprazole
Dapiprazole Brand names, Dapiprazole Analogs
Dapiprazole Brand Names Mixture
- No information avaliable
Dapiprazole Chemical_Formula
C19H27N5
Dapiprazole RX_link
No information avaliable
Dapiprazole fda sheet
Dapiprazole msds (material safety sheet)
Dapiprazole Synthesis Reference
No information avaliable
Dapiprazole Molecular Weight
325.451 g/mol
Dapiprazole Melting Point
No information avaliable
Dapiprazole H2O Solubility
Soluble
Dapiprazole State
Solid
Dapiprazole LogP
No information avaliable
Dapiprazole Dosage Forms
Ophthalmic solution (eye drops, 0.5%); Ophthalmic powder for reconstitution (0.5%)
Dapiprazole Indication
Used in the treatment of iatrogenically induced mydriasis produced by adrenergic (phenylephrine) or parasympatholytic (tropicamide) agents used in certain eye examinations.
Dapiprazole Pharmacology
Dapiprazole is an alpha-adrenergic blocking agent. It produces miosis by blocking the alpha-adrenergic receptors on the dilator muscle of the iris. Dapiprazole produces no significant action on ciliary muscle contraction and thus, there are no changes in the depth of the anterior chamber of the thickness of the lens. It does not alter the IOP either in normal eyes or in eyes with elevated IOP. The rate of pupillary constriction may be slightly slower in clients with brown irises than in clients with blue or green irises.
Dapiprazole Absorption
Systemic absorption is negligible.
Dapiprazole side effects and Toxicity
Oral LD50 is 1189—2100 mg/kg in mice, rats and rabbits.
Dapiprazole Patient Information
Dapiprazole Organisms Affected
Humans and other mammals
