Cyclosporine
Brand names,
Cyclosporine
Analogs
Cyclosporine
Brand Names Mixture
Cyclosporine
Chemical_Formula
C62H111N11O12
Cyclosporine
RX_link
http://www.rxlist.com/cgi/generic3/restasis.htm
Cyclosporine
fda sheet
Cyclosporine
msds (material safety sheet)
Cyclosporine
Synthesis Reference
No information avaliable
Cyclosporine
Molecular Weight
1202.61
Cyclosporine
Melting Point
No information avaliable
Cyclosporine
H2O Solubility
No information avaliable
Cyclosporine
State
Liquid
Cyclosporine
LogP
4.293
Cyclosporine
Dosage Forms
Capsule (liquid-filled); Capsule (liquid-filled for emulsion); Solution (oral); Solution (IV infusion)
Cyclosporine
Indication
For treatment of transplant rejection, rheumatoid arthritis, severe psoriasis
Cyclosporine
Pharmacology
Used in immunosuppression for prophylactic treatment of organ transplants, cyclosporine exerts specific and reversible inhibition of immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited. The T1-helper cell is the main target, although the T1-suppressor cell may also be suppressed. Sandimmune (cyclosporine) also inhibits lymphokine production and release including interleukin-2.
Cyclosporine
Absorption
No information avaliable
Cyclosporine
side effects and Toxicity
No information avaliable
Cyclosporine
Patient Information
BIOD00003.html
Cyclosporine
Organisms Affected
Humans and other mammals