Gengraf (Abbott labs)
Brand names,
Gengraf (Abbott labs)
Analogs
Gengraf (Abbott labs)
Brand Names Mixture
Gengraf (Abbott labs)
Chemical_Formula
C62H111N11O12
Gengraf (Abbott labs)
RX_link
http://www.rxlist.com/cgi/generic3/restasis.htm
Gengraf (Abbott labs)
fda sheet
Gengraf (Abbott labs)
msds (material safety sheet)
Gengraf (Abbott labs)
Synthesis Reference
No information avaliable
Gengraf (Abbott labs)
Molecular Weight
1202.61
Gengraf (Abbott labs)
Melting Point
No information avaliable
Gengraf (Abbott labs)
H2O Solubility
No information avaliable
Gengraf (Abbott labs)
State
Liquid
Gengraf (Abbott labs)
LogP
4.293
Gengraf (Abbott labs)
Dosage Forms
Capsule (liquid-filled); Capsule (liquid-filled for emulsion); Solution (oral); Solution (IV infusion)
Gengraf (Abbott labs)
Indication
For treatment of transplant rejection, rheumatoid arthritis, severe psoriasis
Gengraf (Abbott labs)
Pharmacology
Used in immunosuppression for prophylactic treatment of organ transplants, cyclosporine exerts specific and reversible inhibition of immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited. The T1-helper cell is the main target, although the T1-suppressor cell may also be suppressed. Sandimmune (cyclosporine) also inhibits lymphokine production and release including interleukin-2.
Gengraf (Abbott labs)
Absorption
No information avaliable
Gengraf (Abbott labs)
side effects and Toxicity
No information avaliable
Gengraf (Abbott labs)
Patient Information
BIOD00003.html
Gengraf (Abbott labs)
Organisms Affected
Humans and other mammals