Corotrope
Brand names,
Corotrope
Analogs
Corotrope
Brand Names Mixture
Corotrope
Chemical_Formula
C12H9N3O
Corotrope
RX_link
http://www.rxlist.com/cgi/generic3/milrin.htm
Corotrope
fda sheet
Corotrope
msds (material safety sheet)
Corotrope
Synthesis Reference
No information avaliable
Corotrope
Molecular Weight
211.219 g/mol
Corotrope
Melting Point
>300 oC
Corotrope
H2O Solubility
Slightly soluble
Corotrope
State
Solid
Corotrope
LogP
0.462
Corotrope
Dosage Forms
Liquid
Corotrope
Indication
Indicated for the treatment of congestive heart failure.
Corotrope
Pharmacology
Milrinone, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Corotrope
Absorption
Milrinone is rapidly and almost completely absorbed after oral administration. Bioavailability is 92% (in healthy volunteers).
Corotrope
side effects and Toxicity
LD50 = 0.3 mg/L in rats
Corotrope
Patient Information
No information avaliable
Corotrope
Organisms Affected
Humans and other mammals