Corotrop
Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C12H9N3O
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RX_link
http://www.rxlist.com/cgi/generic3/milrin.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
211.219 g/mol
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Melting Point
>300 oC
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H2O Solubility
Slightly soluble
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State
Solid
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LogP
0.462
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Dosage Forms
Liquid
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Indication
Indicated for the treatment of congestive heart failure.
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Pharmacology
Milrinone, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
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Absorption
Milrinone is rapidly and almost completely absorbed after oral administration. Bioavailability is 92% (in healthy volunteers).
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side effects and Toxicity
LD50 = 0.3 mg/L in rats
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals