Cogentine
Brand names,
Cogentine
Analogs
Cogentine
Brand Names Mixture
Cogentine
Chemical_Formula
C21H25NO
Cogentine
RX_link
http://www.rxlist.com/cgi/generic2/benztrop.htm
Cogentine
fda sheet
Cogentine
msds (material safety sheet)
Cogentine
Synthesis Reference
No information avaliable
Cogentine
Molecular Weight
307.429 g/mol
Cogentine
Melting Point
No information avaliable
Cogentine
H2O Solubility
Very soluble
Cogentine
State
Solid
Cogentine
LogP
4.987
Cogentine
Dosage Forms
Tablet
Cogentine
Indication
For use as an adjunct in the therapy of all forms of parkinsonism and also for use in the control of extrapyramidal disorders due to neuroleptic drugs.
Cogentine
Pharmacology
Benztropine is an anticholinergic used in the symptomatic treatment of all etiologic groups of parkinsonism and drug induced extrapyramidal reactions (except tardive dyskinesia). Benztropine possesses both anticholinergic and antihistaminic effects, although only the former has been established as therapeutically significant in the management of parkinsonism. Benztropine's anticholinergic activity is about equal to that of atropine.
Cogentine
Absorption
No information avaliable
Cogentine
side effects and Toxicity
Signs of overdose include confusion, nervousness, listlessness, hallucinations, dizziness; muscle weakness, ataxia, dry mouth, mydriasis, blurred vision, palpitations, tachycardia, elevated blood pressure, nausea, vomiting, dysuria, numbness of fingers, headache, delirium, coma, shock, convulsions, respiratory arrest, anhidrosis, hyperthermia, glaucoma, and constipation.
Cogentine
Patient Information
No information avaliable
Cogentine
Organisms Affected
Humans and other mammals