Clomocycline
Clomocycline Brand names, Clomocycline Analogs
Clomocycline Brand Names Mixture
- No information avaliable
Clomocycline Chemical_Formula
C23H25ClN2O9
Clomocycline RX_link
No information avaliable
Clomocycline fda sheet
Clomocycline msds (material safety sheet)
Clomocycline Synthesis Reference
No information avaliable
Clomocycline Molecular Weight
508.905 g/mol
Clomocycline Melting Point
No information avaliable
Clomocycline H2O Solubility
No information avaliable
Clomocycline State
Solid
Clomocycline LogP
0.058
Clomocycline Dosage Forms
No information avaliable
Clomocycline Indication
For the treatment and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection;Chronic bronchitis
Clomocycline Pharmacology
Clomocycline is a tetracycline antibiotic that is commonly prescribed by medical doctors for infections and to treat acne. It may also be used to treat urinary tract infections, gum disease, and other bacterial infections such as gonorrhea and chlamydia. Clomocycline is also used commonly as a prophylactic treatment for infection by Bacillus anthracis (anthrax). It is also effective against Yersinia pestis and malaria and is also prescribed for the treatment of Lyme disease. Clomocycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Cells become resistant to Clomocycline by at least two mechanisms: efflux and ribosomal protection. In efflux, a resistance gene encodes a membrane protein that actively pumps Clomocycline out of the cell. This is the mechanism of action of the tetracycline resistance gene on the artificial plasmid pBR322. In ribosomal protection, a resistance gene encodes a protein which binds to the ribosome and prevents Clomocycline from acting on the ribosome.
Clomocycline Absorption
No information avaliable
Clomocycline side effects and Toxicity
No information avaliable
Clomocycline Patient Information
No information avaliable
Clomocycline Organisms Affected
Enteric bacteria and other eubacteria
