Chlormethylenecycline
Chlormethylenecycline Brand names, Chlormethylenecycline Analogs
Chlormethylenecycline Brand Names Mixture
- No information avaliable
Chlormethylenecycline Chemical_Formula
C23H25ClN2O9
Chlormethylenecycline RX_link
No information avaliable
Chlormethylenecycline fda sheet
Chlormethylenecycline msds (material safety sheet)
Chlormethylenecycline Synthesis Reference
No information avaliable
Chlormethylenecycline Molecular Weight
508.905 g/mol
Chlormethylenecycline Melting Point
No information avaliable
Chlormethylenecycline H2O Solubility
No information avaliable
Chlormethylenecycline State
Solid
Chlormethylenecycline LogP
0.058
Chlormethylenecycline Dosage Forms
No information avaliable
Chlormethylenecycline Indication
For the treatment and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection;Chronic bronchitis
Chlormethylenecycline Pharmacology
Clomocycline is a tetracycline antibiotic that is commonly prescribed by medical doctors for infections and to treat acne. It may also be used to treat urinary tract infections, gum disease, and other bacterial infections such as gonorrhea and chlamydia. Clomocycline is also used commonly as a prophylactic treatment for infection by Bacillus anthracis (anthrax). It is also effective against Yersinia pestis and malaria and is also prescribed for the treatment of Lyme disease. Clomocycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Cells become resistant to Clomocycline by at least two mechanisms: efflux and ribosomal protection. In efflux, a resistance gene encodes a membrane protein that actively pumps Clomocycline out of the cell. This is the mechanism of action of the tetracycline resistance gene on the artificial plasmid pBR322. In ribosomal protection, a resistance gene encodes a protein which binds to the ribosome and prevents Clomocycline from acting on the ribosome.
Chlormethylenecycline Absorption
No information avaliable
Chlormethylenecycline side effects and Toxicity
No information avaliable
Chlormethylenecycline Patient Information
No information avaliable
Chlormethylenecycline Organisms Affected
Enteric bacteria and other eubacteria
