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Clofarabine Brand names, Clofarabine Analogs

Clofarabine Brand Names Mixture

  • No information avaliable

Clofarabine Chemical_Formula


Clofarabine RX_link

Clofarabine fda sheet

Clofarabine FDA

Clofarabine msds (material safety sheet)

Clofarabine Synthesis Reference

No information avaliable

Clofarabine Molecular Weight

303.677 g/mol

Clofarabine Melting Point

No information avaliable

Clofarabine H2O Solubility

No information avaliable

Clofarabine State


Clofarabine LogP


Clofarabine Dosage Forms

Solution for intravenous infusion (1 mg/mL, supplied in a 20 mL, single-use vial)

Clofarabine Indication

For the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens.

Clofarabine Pharmacology

Clofarabine is a purine nucleoside antimetabolite. Clofarabine seems to interfere with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells also may be affected by clofarabine, other effects also occur. Clofarabine prevents cells from making DNA and RNA by interfering with the synthesis of nucleic acids, thus stopping the growth of cancer cells.

Clofarabine Absorption

No information avaliable

Clofarabine side effects and Toxicity

There were no known overdoses of clofarabine. The highest daily dose administered to a human to date (on a mg/m2 basis) has been 70 mg/m2/day × 5 days (2 pediatric ALL patients). The toxicities included in these 2 patients included grade 4 hyperbilirubinemia, grade 2 and 3 vomiting, and grade 3 maculopapular rash.

Clofarabine Patient Information

Clofarabine Organisms Affected

Humans and other mammals