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Clolar Brand names, Clolar Analogs

Clolar Brand Names Mixture

  • No information avaliable

Clolar Chemical_Formula


Clolar RX_link

Clolar fda sheet

Clolar FDA

Clolar msds (material safety sheet)

Clolar Synthesis Reference

No information avaliable

Clolar Molecular Weight

303.677 g/mol

Clolar Melting Point

No information avaliable

Clolar H2O Solubility

No information avaliable

Clolar State


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Clolar Dosage Forms

Solution for intravenous infusion (1 mg/mL, supplied in a 20 mL, single-use vial)

Clolar Indication

For the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens.

Clolar Pharmacology

Clofarabine is a purine nucleoside antimetabolite. Clofarabine seems to interfere with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells also may be affected by clofarabine, other effects also occur. Clofarabine prevents cells from making DNA and RNA by interfering with the synthesis of nucleic acids, thus stopping the growth of cancer cells.

Clolar Absorption

No information avaliable

Clolar side effects and Toxicity

There were no known overdoses of clofarabine. The highest daily dose administered to a human to date (on a mg/m2 basis) has been 70 mg/m2/day × 5 days (2 pediatric ALL patients). The toxicities included in these 2 patients included grade 4 hyperbilirubinemia, grade 2 and 3 vomiting, and grade 3 maculopapular rash.

Clolar Patient Information

Clolar Organisms Affected

Humans and other mammals