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Clocortolone Brand names, Clocortolone Analogs

Clocortolone Brand Names Mixture

  • No information avaliable

Clocortolone Chemical_Formula

C27H36ClFO5

Clocortolone RX_link

http://www.rxlist.com/cgi/generic2/clocortolone.htm

Clocortolone fda sheet

Clocortolone FDA

Clocortolone msds (material safety sheet)

Clocortolone Synthesis Reference

No information avaliable

Clocortolone Molecular Weight

495.023 g/mol

Clocortolone Melting Point

No information avaliable

Clocortolone H2O Solubility

No information avaliable

Clocortolone State

Solid

Clocortolone LogP

4.988

Clocortolone Dosage Forms

Cream; Suspension

Clocortolone Indication

For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.

Clocortolone Pharmacology

Like other topical corticosteroids, clocortolone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Clocortolone is a moderate potency topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.

Clocortolone Absorption

Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.

Clocortolone side effects and Toxicity

Topically applied clocortolone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

Clocortolone Patient Information

Clocortolone Organisms Affected

Humans and other mammals