Clocortolone
Clocortolone Brand names, Clocortolone Analogs
Clocortolone Brand Names Mixture
- No information avaliable
Clocortolone Chemical_Formula
C27H36ClFO5
Clocortolone RX_link
http://www.rxlist.com/cgi/generic2/clocortolone.htm
Clocortolone fda sheet
Clocortolone msds (material safety sheet)
Clocortolone Synthesis Reference
No information avaliable
Clocortolone Molecular Weight
495.023 g/mol
Clocortolone Melting Point
No information avaliable
Clocortolone H2O Solubility
No information avaliable
Clocortolone State
Solid
Clocortolone LogP
4.988
Clocortolone Dosage Forms
Cream; Suspension
Clocortolone Indication
For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.
Clocortolone Pharmacology
Like other topical corticosteroids, clocortolone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Clocortolone is a moderate potency topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.
Clocortolone Absorption
Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.
Clocortolone side effects and Toxicity
Topically applied clocortolone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).
Clocortolone Patient Information
Clocortolone Organisms Affected
Humans and other mammals
