Clocortolone pivalate
Clocortolone pivalate Brand names, Clocortolone pivalate Analogs
Clocortolone pivalate Brand Names Mixture
- No information avaliable
Clocortolone pivalate Chemical_Formula
C27H36ClFO5
Clocortolone pivalate RX_link
http://www.rxlist.com/cgi/generic2/clocortolone.htm
Clocortolone pivalate fda sheet
Clocortolone pivalate msds (material safety sheet)
Clocortolone pivalate Synthesis Reference
No information avaliable
Clocortolone pivalate Molecular Weight
495.023 g/mol
Clocortolone pivalate Melting Point
No information avaliable
Clocortolone pivalate H2O Solubility
No information avaliable
Clocortolone pivalate State
Solid
Clocortolone pivalate LogP
4.988
Clocortolone pivalate Dosage Forms
Cream; Suspension
Clocortolone pivalate Indication
For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.
Clocortolone pivalate Pharmacology
Like other topical corticosteroids, clocortolone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Clocortolone is a moderate potency topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.
Clocortolone pivalate Absorption
Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.
Clocortolone pivalate side effects and Toxicity
Topically applied clocortolone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).
Clocortolone pivalate Patient Information
Clocortolone pivalate Organisms Affected
Humans and other mammals
