Choloxin
Brand names,
Choloxin
Analogs
Choloxin
Brand Names Mixture
Choloxin
Chemical_Formula
C24H45NO8
Choloxin
RX_link
No information avaliable
Choloxin
fda sheet
Choloxin
msds (material safety sheet)
Choloxin
Synthesis Reference
No information avaliable
Choloxin
Molecular Weight
475.616 g/mol
Choloxin
Melting Point
100oC
Choloxin
H2O Solubility
0.2 g/mL
Choloxin
State
Solid
Choloxin
LogP
-0.12
Choloxin
Dosage Forms
Liquid; Powder; Solution; Tablet
Choloxin
Indication
Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities incompatible with life. Also used at low-doses for medically indicated induction of labor at term. Also injected intra-arterially for use as a vasodilator to assist in angiography.
Choloxin
Pharmacology
Dinoprost tromethamine is the tromethamine (THAM) salt of the naturally occurring prostaglandin F2alpha. Prostaglandin F2alpha has several pharmacologic effects on the female reproductive system, including stimulation of myometrial activity, relaxation of the cervix, inhibition of steroidogenesis by corpora lutea, and can potentially lyse corpora lutea.
Choloxin
Absorption
Slowly absorbed from the amniotic fluid into systemic circulation.
Choloxin
side effects and Toxicity
Although overdose by intra-amniotic administration of dinoprost has not been reported, exaggeration of the nausea, vomiting, and diarrhea that occur with normal doses would be expected.
Choloxin
Patient Information
No information avaliable
Choloxin
Organisms Affected
Humans and other mammals