UPJOHN CO THE -- 40645 LUTALYSE STERILE SOLUTION -- 6505-00F040296
===================== Product Identification =====================
Product ID:40645 LUTALYSE STERILE SOLUTION
MSDS Date:07/01/1994
FSC:6505
NIIN:00F040296
MSDS Number: BXLJF
=== Responsible Party ===
Company Name:UPJOHN CO THE
Address:7171 PORTAGE RD
City:KALAMAZOO
State:MI
ZIP:49001-0199
Country:US
Info Phone Num:616-385-7358/800-253-8600
Emergency Phone Num:616-323-7555/616-323-5122
CAGE:GO374
=== Contractor Identification ===
Company Name:PHARMACIA & UPJOHN
Address:7171 PORTAGE RD
Box:City:KALAMAZOO
State:MI
ZIP:49001-0199
Country:US
Phone:616-833-5122/616-833-7555
CAGE:93703
Company Name:UPJOHN CO THE
Address:7171 PORTAGE RD
City:KALAMAZOO
State:MI
ZIP:49001-0199
Country:US
Phone:616-323-7555
CAGE:GO374
============= Composition/Information on Ingredients =============
Ingred Name:WATER
CAS:7732-18-5
RTECS #:ZC0110000
Fraction by Wt: 98-98.7%
Ingred Name:BENZYL ALCOHOL
CAS:100-51-6
RTECS #:DN3150000
Fraction by Wt: 0.9-1%
Ingred Name:DINOPROST TROMETHAMINE *95-1*
CAS:38562-01-5
RTECS #:UK8025000
Fraction by Wt: 0.6-0.7%
===================== Hazards Identification =====================
LD50 LC50 Mixture:ORAL LD50(MOUSE): 711 MG/KG (SEE SUPPP)
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:DINOPROST TROMETHAMINE: RESPIRATORY
EFFECTS, IRRITATION, REPRODUCTIVE EFFECTS. LIPOPHILIC
PROSTAGLANDINS IS READILY ABSORBED THROUGH THE SKIN. CHRONIC
EXPOSURE MAY ALSO CAUSE KIDNEY, LIVER, OVARIAN & TESTICULAR
DAMAGE.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:SMOOTH MUSCLE CONTRACTION, BRONCHOCONSTRICTION,
WHEEZING, COUGHING, RAPID BREAHTING, ANAPHYLAXIS, UTERINE
CONTRACTIONS, VAGINAL BLEEDING, UTERINE & URINARY INFECTIONS, GI
DISTURBANCES, ABDOMINAL CRAMP ING, DIARRHEA, VOMITING, NAUSEA,
INCREASED PULSE RATE, ELEVATED BLOOD PRESSURE, CHILLS, FEVER,
ANOREXIA.
Medical Cond Aggravated by Exposure:DINOPROST TROMETHAMINE: ACUTE
PELVIC INFLAMMATORY DISEASE/ACTIVE HEART/LUNG/KIDNEY/LIVER
DISEASE/KNOWN
HYPERSENSITIVITY/ASTHMA/GLAUCOMA/HYPERTENSION/EPILEPSY/CARDIOVASCUL
AR DISEASE.
======================= First Aid Measures =======================
First Aid:EYES: FLUSH W/WATER FOR 15 MINS. SKIN: WASH W/SOAP & WATER.
INHALATION: REMOVE TO FRESH AIR. OBTAIN MEDICAL ATTENTION IN ALL
CASES. NOTES TO PHYSICIAN: THE TIME OF ONSET & DURATION OF SYMPTOMS
RESULTI NG FROM ACCIDENTAL OVEREXPOSURE IS EXPECTED TO BE
RELATIVELY RAPID. THE BIOLOGICAL HALF LIFE OF DINOPROST
TROMETHAMINE IS NO MORE THAN A FEW MINS.
===================== Fire Fighting Measures =====================
Flash Point:NONFLAMMABLE
Extinguishing Media:WATER, CO2, DRY CHEMICAL
Fire Fighting Procedures:WEAR SCBA & FULL BODY PROTECTIVE EQUIPMENT.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR APPROPRIATE PROTECTIVE EQUIPMENT. ABSORB
LIQUID ON PAPER TOWELS/OTHER APPROPRIATE MEDIA. WASH SITE W/DILUTE
BLEACH WHEN MATERIAL PICKUP IS COMPLETE. DINOPROST TROMETHAMINE CAN
BE INACTIVATED IN D ILUTE BLEACH.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE IN A COOL DRY PLACE. PROTECT
FROM LIGHT.
Other Precautions:KEEP OUT OF REACH OF CHILDREN. PREGNANT FEMALES
SHOULD AVOID ALL EXPOSURE.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:AN APPROVED RESPIRATOR IF SPLASHED, MIST/AEROSOL
GENERATION.
Ventilation:LOCAL EXHAUST
Protective Gloves:RUBBER
Eye Protection:SAFETY GLASSES W/SIDE SHIELDS
Other Protective Equipment:PROTECTIVE COVERING FOR EXPOSED AREAS OF
SKIN.
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE. WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
USE PROTECTIVE EQUIPMENT & GOOD WORK PRACTICES TO AVOID EXPOSURE. PH:
7.8-8.2.
================== Physical/Chemical Properties ==================
Melt/Freeze Pt:M.P/F.P Text:32F
Spec Gravity:0.996-1.004
pH:(SUPP)
Solubility in Water:COMPLETE
Appearance and Odor:CLEAR LIQUID
Percent Volatiles by Volume:99.5
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
NONE
Stability Condition to Avoid:LIGHT
Hazardous Decomposition Products:CO, CO2
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE/INCINERATE IAW/FEDERAL, STATE & LOCAL
REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.