PharmacyCodes



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Apropovir Brand names, Apropovir Analogs

Apropovir Brand Names Mixture

  • No information avaliable

Apropovir Chemical_Formula

C8H13N3O4S

Apropovir RX_link

No information avaliable

Apropovir fda sheet

Apropovir FDA

Apropovir msds (material safety sheet)

Apropovir MSDS

Apropovir Synthesis Reference

No information avaliable

Apropovir Molecular Weight

247.273 g/mol

Apropovir Melting Point

127-128 oC

Apropovir H2O Solubility

1.99E+004 mg/L

Apropovir State

Solid

Apropovir LogP

0.119

Apropovir Dosage Forms

Pink film-coated oral tablets contain 500 mg or 250 mg of tinidazole.

Apropovir Indication

For the treatment of trichomoniasis caused by T. vaginalis in both female and male patients. Also for the treatment of giardiasis caused by G. duodenalis in both adults and pediatric patients older than three years of age and for the treatment of intestinal amebiasis and amebic liver abscess caused by E. histolytica in both adults and pediatric patients older than three years of age.

Apropovir Pharmacology

Tinidazole is a synthetic antiprotozoal agent. Tinidazole demonstrates activity both in vitro and in clinical infections against the following protozoa: Trichomonas vaginalis, Giardia duodenalis (also termed G. lamblia), and Entamoeba histolytica. Tinidazole does not appear to have activity against most strains of vaginal lactobacilli.

Apropovir Absorption

Rapidly and completely absorbed under fasting conditions. Administration with food results in a delay in Tmax of approximately 2 hours and a decline in Cmax of approximately 10% and an AUC of 901.6 ± 126.5 mcg hr/mL.

Apropovir side effects and Toxicity

There are no reported overdoses with tinidazole in humans. In acute studies with mice and rats, the LD 50 for mice was generally > 3,600 mg/kg for oral administration and was > 2,300 mg/kg for intraperitoneal administration. In rats, the LD 50 was > 2,000 mg/kg for both oral and intraperitoneal administration.

Apropovir Patient Information

Apropovir Organisms Affected

Trichomonas vaginalis, Giardia duodenalis (also termed G. lamblia), and Entamoeba histolytica