Antibiotic SM 7338

Antibiotic SM 7338 Brand names, Antibiotic SM 7338 Analogs

Antibiotic SM 7338 Brand Names Mixture

No information avaliable

Antibiotic SM 7338 Chemical_Formula

C₉H₁₁Cl₂N₃O₄S₂

Antibiotic SM 7338 RX_link

http://www.rxlist.com/cgi/generic3/methyclothiazide.htm

Antibiotic SM 7338 fda sheet

Antibiotic SM 7338 msds (material safety sheet)

Antibiotic_SM_7338 MSDS

Antibiotic SM 7338 Synthesis Reference

No information avaliable

Antibiotic SM 7338 Molecular Weight

360.239 g/mol

Antibiotic SM 7338 Melting Point

225 ^oC

Antibiotic SM 7338 H₂O Solubility

11.2 mg/L

Antibiotic SM 7338 State

Solid

Antibiotic SM 7338 LogP

0.604

Antibiotic SM 7338 Dosage Forms

Tablet for oral administration (5 mg)

Antibiotic SM 7338 Indication

For use in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension. Also used as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.

Antibiotic SM 7338 Pharmacology

Methyclothiazide, a diuretic-antihypertensive agent, is a member of the benzothiadiazine (thiazide) class of drugs. Methyclothiazide has a per mg natriuretic activity approximately 100 times that of the prototype thiazide, chlorothiazide. At maximal therapeutic dosages, all thiazides are approximately equal in their diuretic/natriuretic effects. Like other benzothiadiazines, methyclothiazide also has antihypertensive properties, and may be used for this purpose either alone or to enhance the antihypertensive action of other drugs.

Antibiotic SM 7338 Absorption

Rapidly absorbed following oral administration.

Antibiotic SM 7338 side effects and Toxicity

Acute oral toxicity (LD₅₀): >4000 mg/kg [Rat]. Symptoms of overdosage include electrolyte imbalance and signs of potassium deficiency such as confusion, dizziness, muscular weakness, and gastrointestinal disturbances.

Antibiotic SM 7338 Patient Information