Antibiotic Ad 32 en es it fr

Antibiotic Ad 32 Brand names, Antibiotic Ad 32 Analogs

Antibiotic Ad 32 Brand Names Mixture

  • No information avaliable

Antibiotic Ad 32 Chemical_Formula

C34H36F3NO13

Antibiotic Ad 32 RX_link

http://www.rxlist.com/cgi/generic2/rubicin.htm

Antibiotic Ad 32 fda sheet

Antibiotic_Ad_32 FDA

Antibiotic Ad 32 msds (material safety sheet)

Antibiotic Ad 32 Synthesis Reference

No information avaliable

Antibiotic Ad 32 Molecular Weight

723.644 g/mol

Antibiotic Ad 32 Melting Point

116-117oC

Antibiotic Ad 32 H2O Solubility

insoluble

Antibiotic Ad 32 State

Solid

Antibiotic Ad 32 LogP

3.332

Antibiotic Ad 32 Dosage Forms

Liquid

Antibiotic Ad 32 Indication

Bladder cancer

Antibiotic Ad 32 Pharmacology

When 800 mg Valstar was administered intravesically to patients with carcinoma in situ, Valstar penetrated into the bladder wall. The mean total anthracycline concentration measured in bladder tissue exceeded the levels causing 90% cytoxicity to human bladder cells cultured in vitro. During the two-hour dose-retention period, the metabolism of Valstar to its major metabolites N-trifluoroacetyladriamycin and N-trifluoroacetyladriamycinol was neglible. After retention, the drug was almost completely excreted by voiding the instillate. Mean percent recovery of Valstar, N-trifluoroacetyladriamycin, and total anthracyclines in 14 urine samples from six patients was 98.6%, 0.4%, and 99.0% of the total administered drug, respectively. During the two-hour dose-retention period, only nanogram quantities of Valstar were absorbed into the plasma.

Antibiotic Ad 32 Absorption

No information avaliable

Antibiotic Ad 32 side effects and Toxicity

No information avaliable

Antibiotic Ad 32 Patient Information

Antibiotic Ad 32 Organisms Affected

Humans and other mammals