PharmacyCodes



Anti EGFR en es it fr

Anti EGFR Brand names, Anti EGFR Analogs

Anti EGFR Brand Names Mixture

  • Actinac Pwr (Allantoin + Butoxyethyl Nicotinate + Chloramphenicol + Hydrocortisone Acetate + Sulfur)
  • Actinac Pws (Allantoin + Butoxyethyl Nicotinate + Chloramphenicol + Hydrocortisone Acetate + Sulfur)
  • Chlorasone (Chloramphenicol + Prednisolone Acetate)
  • Elase Chloromycetin Ont (Chloramphenicol + Deoxyribonuclease Pancreatic + Fibrinolysin)
  • Liquichlor (Chloramphenicol + Prednisolone + Squalane + Tetracaine)
  • Ophthocort Ont (Chloramphenicol + Hydrocortisone Acetate + Polymyxin B)
  • Sopamycetin/Hc Ointment (Chloramphenicol + Hydrocortisone Acetate)
  • Sopamycetin/Hc Ont (Chloramphenicol + Hydrocortisone Acetate)
  • Sopamycetin/Hc Susp (Chloramphenicol + Hydrocortisone Acetate)
  • Zoomycetine Spray (Chloramphenicol + Isopropyl Alcohol + Methyl Violet)

Anti EGFR Chemical_Formula

C6484H10042N1732O2023S36

Anti EGFR RX_link

http://www.rxlist.com/cgi/generic3/erbitux.htm

Anti EGFR fda sheet

Anti_EGFR FDA

Anti EGFR msds (material safety sheet)

Anti EGFR Synthesis Reference

sequence listed in Goldstein N. I., Prewett M., Zuklys K., Rockwell P., Mendelsohn J. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin. Cancer Res., 1: 1311-1318, 1995.) patent 6,217,866

Anti EGFR Molecular Weight

145781.6

Anti EGFR Melting Point

61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

Anti EGFR H2O Solubility

No information avaliable

Anti EGFR State

Liquid

Anti EGFR LogP

-0.413

Anti EGFR Dosage Forms

Solution (IV Infusion)

Anti EGFR Indication

For treatment of metastatic colorectal cancer

Anti EGFR Pharmacology

Used in the treatment of colorectal cancer, Erbitux binds specifically to the epidermal growth factor receptor (EGFr, HER1, c-ErbB-1) on both normal and tumor cells. EGFr is over-expressed in many colorectal cancers. Erbitux competitively inhibits the binding of epidermal growth factor (EGF) and other ligands, such as transforming growth factor??“alpha. Binding of Erbitux to the EGFr blocks phosphorylation and activation of receptor-associated kinases, resulting in inhibition of cell growth, induction of apoptosis, decreased matrix metalloproteinase secretion and reduced vascular endothelial growth factor production.

Anti EGFR Absorption

No information avaliable

Anti EGFR side effects and Toxicity

No information avaliable

Anti EGFR Patient Information

No information avaliable

Anti EGFR Organisms Affected

Humans and other mammals