Antagon 

• Fertility Agents, Female
• ATC:H01CA01
• ATC:V04CM01

• Antagon 
• Ganirelix Acetate
• Ganirelix Acetate Injection
• Orgalutran

• No information avaliable

C₅₅H₇₅N₁₇O₁₃

http://www.rxlist.com/cgi/generic2/gonadorelin.htm

Antagon  MSDS

No information avaliable

1182.29 g/mol

No information avaliable

1 mg/mL

Liquid

-4.634

Liquid; Powder for solution; Solution for infusion pump

For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.

Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use

Rapidly absorbed when injected

LD₅₀>3000 mg/kg (rat, oral)

Humans and other mammals