Anisotropine methobromide
Brand names,
Anisotropine methobromide
Analogs
Anisotropine methobromide
Brand Names Mixture
Anisotropine methobromide
Chemical_Formula
C17H32BrNO2
Anisotropine methobromide
RX_link
No information avaliable
Anisotropine methobromide
fda sheet
Anisotropine methobromide
msds (material safety sheet)
Anisotropine methobromide
Synthesis Reference
No information avaliable
Anisotropine methobromide
Molecular Weight
362.346 g/mol
Anisotropine methobromide
Melting Point
329 oC
Anisotropine methobromide
H2O Solubility
1600 mg/L
Anisotropine methobromide
State
Solid
Anisotropine methobromide
LogP
0.60
Anisotropine methobromide
Dosage Forms
Tablet (oral, 50mg)
Anisotropine methobromide
Indication
For use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying.
Anisotropine methobromide
Pharmacology
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and gallbladder. In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate. Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to inhibit gastric acid secretion.
Anisotropine methobromide
Absorption
Gastrointestinal absorption is poor and irregular. Total absorption after an oral dose is about 10 to 25%.
Anisotropine methobromide
side effects and Toxicity
No information avaliable
Anisotropine methobromide
Patient Information
Anisotropine methobromide
Organisms Affected
Humans and other mammals