Amprenavir
Brand names,
Amprenavir
Analogs
Amprenavir
Brand Names Mixture
Amprenavir
Chemical_Formula
C25H35N3O6S
Amprenavir
RX_link
http://www.rxlist.com/cgi/generic2/ampren.htm
Amprenavir
fda sheet
Amprenavir
msds (material safety sheet)
Amprenavir
Synthesis Reference
No information avaliable
Amprenavir
Molecular Weight
505.628 g/mol
Amprenavir
Melting Point
No information avaliable
Amprenavir
H2O Solubility
No information avaliable
Amprenavir
State
Solid
Amprenavir
LogP
2.064
Amprenavir
Dosage Forms
Capsule
Amprenavir
Indication
For the treatment of HIV-1 infection in combination with other antiretroviral agents.
Amprenavir
Pharmacology
Amprenavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Amprenavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.
Amprenavir
Absorption
No information avaliable
Amprenavir
side effects and Toxicity
No information avaliable
Amprenavir
Patient Information
Amprenavir
Organisms Affected
Human immunodeficiency virus