Lexiva
Brand names,
Lexiva
Analogs
Lexiva
Brand Names Mixture
Lexiva
Chemical_Formula
C25H35N3O6S
Lexiva
RX_link
http://www.rxlist.com/cgi/generic2/ampren.htm
Lexiva
fda sheet
Lexiva
msds (material safety sheet)
Lexiva
Synthesis Reference
No information avaliable
Lexiva
Molecular Weight
505.628 g/mol
Lexiva
Melting Point
No information avaliable
Lexiva
H2O Solubility
No information avaliable
Lexiva
State
Solid
Lexiva
LogP
2.064
Lexiva
Dosage Forms
Capsule
Lexiva
Indication
For the treatment of HIV-1 infection in combination with other antiretroviral agents.
Lexiva
Pharmacology
Amprenavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Amprenavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.
Lexiva
Absorption
No information avaliable
Lexiva
side effects and Toxicity
No information avaliable
Lexiva
Patient Information
Lexiva
Organisms Affected
Human immunodeficiency virus