Alrex
Brand names,
Alrex
Analogs
Alrex
Brand Names Mixture
Alrex
Chemical_Formula
C19H32N2O5
Alrex
RX_link
http://www.rxlist.com/cgi/generic/aceon.htm
Alrex
fda sheet
Alrex
msds (material safety sheet)
Alrex
Synthesis Reference
No information avaliable
Alrex
Molecular Weight
368.468 g/mol
Alrex
Melting Point
No information avaliable
Alrex
H2O Solubility
No information avaliable
Alrex
State
No information avaliable
Alrex
LogP
2.633
Alrex
Dosage Forms
Tablet
Alrex
Indication
Used in patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.
Alrex
Pharmacology
Perindopril is indicated in patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction. It can be used with conventional treatment for management of coronary artery disease, such as antiplatelet, antihypertensive or lipid-lowering therapy. It is also indicated for the treatment of patients with essential hypertension. Perindopril belongs to a group of medicines called ACE inhibitors which block the action of a chemical in the body called angiotensin converting enzyme (ACE). Normally ACE produces another chemical, angiotensin. Thus perindopril reduces the amount of angiotensin in the blood. Angiotensin has two actions. Firstly it acts on blood vessels to make them narrow and secondly it acts on the kidney to produce less urine. As perindopril stops the production of angiotensin, these actions are reversed. Therefore more urine is produced by the kidneys, which results in less fluid in the blood vessels. The blood vessels also widen. The overall effect of this is a drop in blood pressure and a decrease in the workload of the heart.
Alrex
Absorption
Rapid
Alrex
side effects and Toxicity
No information avaliable
Alrex
Patient Information
No information avaliable
Alrex
Organisms Affected
Humans and other mammals