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Alphagan Brand names, Alphagan Analogs

Alphagan Brand Names Mixture

  • None

Alphagan Chemical_Formula


Alphagan RX_link

Alphagan fda sheet

Alphagan FDA

Alphagan msds (material safety sheet)

Alphagan MSDS

Alphagan Synthesis Reference

M. B. Thomas, M. T. Williams, Ger. Pat. 2,538,630 (1976 to Pfizer)

Alphagan Molecular Weight

292.135 g/mol

Alphagan Melting Point

207.5 oC

Alphagan H2O Solubility

Soluble (1.5 mg/mL)

Alphagan State


Alphagan LogP


Alphagan Dosage Forms

0.2% solution

Alphagan Indication

For the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Alphagan Pharmacology

Brimonidine significantly lowers intraocular pressure with minimal effects on cardiovascular and pulmonary parameters. It lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow.

Alphagan Absorption

Minimal systemic absorption occurs after ocular insertion.

Alphagan side effects and Toxicity

Oral LD50 is 50 mg/kg in mice and 100 mg/kg in rats.

Alphagan Patient Information

Brimonidine tartrate is used for the treatment of open-angle glaucoma and ocular hypertension. Do not take this drug if you are currently taking MAO Inhibitors (e.g., Parnate). Inform your doctor if you are pregnant or nursing.
This product may stain soft contact lenses. Wait at least 15 minutes after instilling brimonidine to insert contact lenses.
May cause drowsiness or tiredness; use caution while driving or operating hazardous machinery. May cause dry mouth, blurring, stinging, or burning of the eyes; headaches, fatigue or drowsiness; allergic or itching of the eyes. Tell your doctor or pharmacist if these effects occur.

Alphagan Organisms Affected

Humans and other mammals