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Aggrastat Brand names, Aggrastat Analogs

Aggrastat Brand Names Mixture

  • No information avaliable

Aggrastat Chemical_Formula

C22H36N2O5S

Aggrastat RX_link

http://www.rxlist.com/cgi/generic/tiro.htm

Aggrastat fda sheet

Aggrastat FDA

Aggrastat msds (material safety sheet)

Aggrastat Synthesis Reference

No information avaliable

Aggrastat Molecular Weight

440.598 g/mol

Aggrastat Melting Point

No information avaliable

Aggrastat H2O Solubility

Very slightly soluble

Aggrastat State

Solid

Aggrastat LogP

3.54

Aggrastat Dosage Forms

Liquid; Solution

Aggrastat Indication

For treatment, in combination with heparin, of acute coronary syndrome, including patients who are to be managed medically and those undergoing PTCA or atherectomy.

Aggrastat Pharmacology

Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation. When administered intravenously, tirofiban inhibits ex vivo platelet aggregation in a dose- and concentration-dependent manner. When given according to the recommended regimen, >90% inhibition is attained by the end of the 30-minute infusion. Tirofiban has been recently shown in patients with unstable angina to reduce ischemic events at 48 hours following infusion when compared to standard heparin therapy.

Aggrastat Absorption

No information avaliable

Aggrastat side effects and Toxicity

No information avaliable

Aggrastat Patient Information

Follow all instructions for proper mixing or dilution (if necessary) and refer to the tirofiban dosing chart for the recommended IV dosing. If you have questions regarding the use of this medication, consult your pharmacist. Give this medication by vein (IV) as an initial dose (bolus dose) followed by an IV infusion as directed by your doctor. The dosage is based on your weight, medical condition, and response to therapy. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Aggrastat Organisms Affected

Humans and other mammals