Aclovate
Brand names,
Aclovate
Analogs
Aclovate
Brand Names Mixture
Aclovate
Chemical_Formula
C28H37ClO7
Aclovate
RX_link
http://www.rxlist.com/cgi/generic3/alclometasone.htm
Aclovate
fda sheet
Aclovate
msds (material safety sheet)
Aclovate
Synthesis Reference
No information avaliable
Aclovate
Molecular Weight
521.042 g/mol
Aclovate
Melting Point
No information avaliable
Aclovate
H2O Solubility
Insoluble
Aclovate
State
Solid
Aclovate
LogP
3.669
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Dosage Forms
Cream (0.5 mg alclometasone/1g cream); Ointment (0.5 mg alclometasone/1g ointment)
Aclovate
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Aclovate
Pharmacology
Alclometasone is a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents. Alclometasone is a selective glucocorticoid receptor agonist.
Aclovate
Absorption
Topical corticosteroids can be absorbed from normal intact skin. Studies have shown that approximately 3% of steroid is absorbed during 8 hours of contact with intact skin of normal volunteers.
Aclovate
side effects and Toxicity
Symptoms of overdose include suppression of adrenal glands, temporary decrease in white blood cell counts, symptoms of hypersensitivity (such as skin rash, hives, itching, and difficulty breathing), and increased susceptibility to infection.
Aclovate
Patient Information
No information avaliable
Aclovate
Organisms Affected
Humans and other mammals