1H-Indole-3-propanoic acid, a-amino-, (S)-
Brand names,
1H-Indole-3-propanoic acid, a-amino-, (S)-
Analogs
1H-Indole-3-propanoic acid, a-amino-, (S)-
Brand Names Mixture
1H-Indole-3-propanoic acid, a-amino-, (S)-
Chemical_Formula
C11H12N2O2
1H-Indole-3-propanoic acid, a-amino-, (S)-
RX_link
No information avaliable
1H-Indole-3-propanoic acid, a-amino-, (S)-
fda sheet
1H-Indole-3-propanoic acid, a-amino-, (S)-
msds (material safety sheet)
1H-Indole-3-propanoic acid, a-amino-, (S)-
Synthesis Reference
No information avaliable
1H-Indole-3-propanoic acid, a-amino-, (S)-
Molecular Weight
204.228 g/mol
1H-Indole-3-propanoic acid, a-amino-, (S)-
Melting Point
280-285 oC
1H-Indole-3-propanoic acid, a-amino-, (S)-
H2O Solubility
Soluble
1H-Indole-3-propanoic acid, a-amino-, (S)-
State
Solid
1H-Indole-3-propanoic acid, a-amino-, (S)-
LogP
-1.429
1H-Indole-3-propanoic acid, a-amino-, (S)-
Dosage Forms
Capsules, Tablets
1H-Indole-3-propanoic acid, a-amino-, (S)-
Indication
Tryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight.
1H-Indole-3-propanoic acid, a-amino-, (S)-
Pharmacology
Tryptophan is critical for the production of the body's proteins, enzymes and muscle tissue. It is also essential for the production of niacin, the synthesis of the neurotransmitter serotonin and melatonin. Tryptophan supplements can be used as natural relaxants to help relieve insomnia. Tryptophan can also reduce anxiety and depression and has been shown to reduce the intensity of migraine headaches. Other promising indications include the relief of chronic pain, reduction of impulsivity or mania and the treatment of obsessive or compulsive disorders. Tryptophan also appears to help the immune system and can reduce the risk of cardiac spasms. Tryptophan deficiencies may lead to coronary artery spasms. Tryptophan is used as an essential nutrient in infant formulas and intravenous feeding. Tryptophan is marketed as a prescription drug (Tryptan) for those who do not seem to respond well to conventional antidepressants. It may also be used to treat those afflicted with seasonal affective disorder (a winter-onset depression). Tryptopan serves as the precursor for the synthesis of serotonin (5-hydroxytryptamine, 5-HT) and melatonin (N-acetyl-5-methoxytryptamine).
1H-Indole-3-propanoic acid, a-amino-, (S)-
Absorption
No information avaliable
1H-Indole-3-propanoic acid, a-amino-, (S)-
side effects and Toxicity
Oral rat LD50: > 16 gm/kg. Investigated as a tumorigen, mutagen, reproductive effector. Symptoms of overdose include agitation, confusion, diarrhea, fever, overactive reflexes, poor coordination, restlessness, shivering, sweating, talking or acting with excitement you cannot control, trembling or shaking, twitching, and vomiting.
1H-Indole-3-propanoic acid, a-amino-, (S)-
Patient Information
It is important that your doctor check your progress at regular visits, to allow dosage adjustments and help reduce any side effects.
1H-Indole-3-propanoic acid, a-amino-, (S)-
Organisms Affected
Humans and other mammals