Vincaleucoblastine

Vincaleucoblastine Brand names, Vincaleucoblastine Analogs

Vincaleucoblastine Brand Names Mixture

No information avaliable

Vincaleucoblastine Chemical_Formula

C₄₆H₅₈N₄O₉

Vincaleucoblastine RX_link

http://www.rxlist.com/cgi/generic3/vinblastine.htm

Vincaleucoblastine fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=29

Vincaleucoblastine msds (material safety sheet)

Vincaleucoblastine MSDS

Vincaleucoblastine Synthesis Reference

No information avaliable

Vincaleucoblastine Molecular Weight

810.974 g/mol

Vincaleucoblastine Melting Point

267 ^oC

Vincaleucoblastine H₂O Solubility

Negligible

Vincaleucoblastine State

Solid

Vincaleucoblastine LogP

5.587

Vincaleucoblastine Dosage Forms

Liquid; Powder for solution; Solution

Vincaleucoblastine Indication

For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.

Vincaleucoblastine Pharmacology

Vinblastine is a vinca alkaloid antineoplastic agent. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units: vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinblastine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Vincaleucoblastine Absorption