Alfacet

Alfacet Brand names, Alfacet Analogs

Alfacet Brand Names Mixture

No information avaliable

Alfacet Chemical_Formula

C₁₅H₁₄ClN₃O₄S

Alfacet RX_link

http://www.rxlist.com/cgi/generic/cefaclor.htm

Alfacet fda sheet

Alfacet FDA

Alfacet msds (material safety sheet)

Alfacet MSDS

Alfacet Synthesis Reference

R. R. Chauvette, U.S. Pat. 3,925,372 (1975)

Alfacet Molecular Weight

367.808 g/mol

Alfacet Melting Point

327 ^oC

Alfacet H₂O Solubility

8.6 mg/mL

Alfacet State

Solid

Alfacet LogP

0.517

Alfacet Dosage Forms

Capsule; Powder; Powder for solution; Powder for suspension; Suspension

Alfacet Indication

For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.

Alfacet Pharmacology

Cefaclor is a second generation cephalosporin antibiotic with a spectrum resembling first-generation cephalosporins. In vitro tests demonstrate that the bactericidal action of the cephalosporins results from inhibition of cell-wall synthesis. Cefaclor has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Gram positive aerobes - Staphylococci (including coagulase-positive, coagulase-negative, and penicillinase-producing strains), Streptococcus pneumoniae, and Streptococcus pyogenes (group A ß-hemolytic streptococci). Gram-negative aerobes - Escherichia coli, Haemophilus influenzae (including ß-lactamase-producing ampicillin-resistant strains), Klebsiella sp, and Proteus mirabilis.

Alfacet Absorption

Well absorbed after oral administration, independent of food intake.

Alfacet side effects and Toxicity

Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.

Alfacet Patient Information

Patients should be counseled that antibacterial drugs including Ceclor should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Ceclor is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Ceclor or other antibacterial drugs in the future.

Alfacet Organisms Affected

Enteric bacteria and other eubacteria