Kefral

Category

Kefral




Useful info

Kefral Brand names, Kefral Analogs

Kefral Brand Names Mixture

  • No information avaliable

    • Kefral Chemical_Formula

    C15H14ClN3O4S

    Kefral RX_link

    http://www.rxlist.com/cgi/generic/cefaclor.htm

    Kefral fda sheet

    Kefral FDA

    Kefral msds (material safety sheet)

    Kefral MSDS

    Kefral Synthesis Reference

    R. R. Chauvette, U.S. Pat. 3,925,372 (1975)

    Kefral Molecular Weight

    367.808 g/mol

    Kefral Melting Point

    327 oC

    Kefral H2O Solubility

    8.6 mg/mL

    Kefral State

    Solid

    Kefral LogP

    0.517

    Kefral Dosage Forms

    Capsule; Powder; Powder for solution; Powder for suspension; Suspension

    Kefral Indication

    For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.

    Kefral Pharmacology

    Cefaclor is a second generation cephalosporin antibiotic with a spectrum resembling first-generation cephalosporins. In vitro tests demonstrate that the bactericidal action of the cephalosporins results from inhibition of cell-wall synthesis. Cefaclor has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Gram positive aerobes - Staphylococci (including coagulase-positive, coagulase-negative, and penicillinase-producing strains), Streptococcus pneumoniae, and Streptococcus pyogenes (group A ß-hemolytic streptococci). Gram-negative aerobes - Escherichia coli, Haemophilus influenzae (including ß-lactamase-producing ampicillin-resistant strains), Klebsiella sp, and Proteus mirabilis.

    Kefral Absorption

    Well absorbed after oral administration, independent of food intake.

    Kefral Toxicity

    Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.

    Kefral Patient Information

    Patients should be counseled that antibacterial drugs including Ceclor should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Ceclor is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Ceclor or other antibacterial drugs in the future.

    Kefral Organisms Affected

    Enteric bacteria and other eubacteria