Pyridoxol hydrochloride

• Anti-inflammatory Agents
• Essential Vitamin
• Vitamins (Vitamin B Complex)
• ATC:A11HA02

• Adermin hydrochloride
• Adermine hydrochloride
• Aderomine hydrochloride
• Aderoxine
• Alestrol
• Becilan
• Beesix
• Benadon
• Bonasanit
• Campoviton 6
• Gravidox
• Hexa-Betalin
• Hexabione hydrochloride
• Hexavibex
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• Hexermine
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• Nestrex
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• Pyridipca
• Pyridox
• Pyridoxal
• Pyridoxamine
• Pyridoxin hydrochloride
• Pyridoxine Chloride
• Pyridoxine HCl
• Pyridoxine hydrochloride
• Pyridoxine hydrogen chloride
• Pyridoxine-HCl Microencapsulated
• Pyridoxinium Chloride
• Pyridoxinum Hydrochloricum
• Pyridoxol hydrochloride
• Rodex TD
• Tex Six T.R.
• Vitamin B
• Vitamin B6 hydrochloride

• No information avaliable

C₈H₁₁NO₃

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Pyridoxol_hydrochloride MSDS

No information avaliable

169.178 g/mol

207 ^oC

2.2E+005 mg/L

Solid

-0.784

Capsules

For the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.

Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.

Readily absorbed

Oral Rat LD₅₀ = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.

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Humans and other mammals