Adermin hydrochloride en es it fr

Category

Adermin_hydrochloride
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Adermin hydrochloride Brand names, Adermin hydrochloride Analogs

Adermin hydrochloride Brand Names Mixture

  • No information avaliable

Adermin hydrochloride Chemical_Formula

C8H11NO3

Adermin hydrochloride RX_link

No information avaliable

Adermin hydrochloride fda sheet

Adermin hydrochloride msds (material safety sheet)

Adermin_hydrochloride MSDS

Adermin hydrochloride Synthesis Reference

No information avaliable

Adermin hydrochloride Molecular Weight

169.178 g/mol

Adermin hydrochloride Melting Point

207 oC

Adermin hydrochloride H2O Solubility

2.2E+005 mg/L

Adermin hydrochloride State

Solid

Adermin hydrochloride LogP

-0.784

Adermin hydrochloride Dosage Forms

Capsules

Adermin hydrochloride Indication

For the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.

Adermin hydrochloride Pharmacology

Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.

Adermin hydrochloride Absorption

Readily absorbed

Adermin hydrochloride side effects and Toxicity

Oral Rat LD50 = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.

Adermin hydrochloride Patient Information

No information avaliable

Adermin hydrochloride Organisms Affected

Humans and other mammals