Propoxyphene en es it fr

Propoxyphene Brand names, Propoxyphene Analogs

Propoxyphene Brand Names Mixture

  • No information avaliable

Propoxyphene Chemical_Formula

C22H29NO2

Propoxyphene RX_link

http://www.rxlist.com/cgi/generic/propox.htm

Propoxyphene fda sheet

Propoxyphene msds (material safety sheet)

Propoxyphene MSDS

Propoxyphene Synthesis Reference

Pohland, U.S. Pat. 2,728,779 (1955)

Propoxyphene Molecular Weight

339.471 g/mol

Propoxyphene Melting Point

75-76oC

Propoxyphene H2O Solubility

19.6mg/L

Propoxyphene State

Solid

Propoxyphene LogP

4.901

Propoxyphene Dosage Forms

Tablet

Propoxyphene Indication

For the relief of mild to moderate pain

Propoxyphene Pharmacology

Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.

Propoxyphene Absorption

No information avaliable

Propoxyphene side effects and Toxicity

Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)

Propoxyphene Patient Information

Propoxyphene Organisms Affected

Humans and other mammals