Doloxen
Doloxen Brand names, Doloxen Analogs
Doloxen Brand Names Mixture
- No information avaliable
Doloxen Chemical_Formula
C22H29NO2
Doloxen RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Doloxen fda sheet
Doloxen msds (material safety sheet)
Doloxen Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Doloxen Molecular Weight
339.471 g/mol
Doloxen Melting Point
75-76oC
Doloxen H2O Solubility
19.6mg/L
Doloxen State
Solid
Doloxen LogP
4.901
Doloxen Dosage Forms
Tablet
Doloxen Indication
For the relief of mild to moderate pain
Doloxen Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Doloxen Absorption
No information avaliable
Doloxen side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Doloxen Patient Information
Doloxen Organisms Affected
Humans and other mammals
