D-Propoxyphene en es it fr

D-Propoxyphene Brand names, D-Propoxyphene Analogs

D-Propoxyphene Brand Names Mixture

  • No information avaliable

D-Propoxyphene Chemical_Formula

C22H29NO2

D-Propoxyphene RX_link

http://www.rxlist.com/cgi/generic/propox.htm

D-Propoxyphene fda sheet

D-Propoxyphene msds (material safety sheet)

D-Propoxyphene MSDS

D-Propoxyphene Synthesis Reference

Pohland, U.S. Pat. 2,728,779 (1955)

D-Propoxyphene Molecular Weight

339.471 g/mol

D-Propoxyphene Melting Point

75-76oC

D-Propoxyphene H2O Solubility

19.6mg/L

D-Propoxyphene State

Solid

D-Propoxyphene LogP

4.901

D-Propoxyphene Dosage Forms

Tablet

D-Propoxyphene Indication

For the relief of mild to moderate pain

D-Propoxyphene Pharmacology

Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.

D-Propoxyphene Absorption

No information avaliable

D-Propoxyphene side effects and Toxicity

Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)

D-Propoxyphene Patient Information

D-Propoxyphene Organisms Affected

Humans and other mammals