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Phosphomycin
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Phosphomycin Brand names, Phosphomycin Analogs

Phosphomycin Brand Names Mixture

  • Micardis Plus (Hydrochlorothiazide + Telmisartan)

Phosphomycin Chemical_Formula

C3H7O4P

Phosphomycin RX_link

http://www.rxlist.com/cgi/generic2/fosfomycin.htm

Phosphomycin fda sheet

Phosphomycin FDA

Phosphomycin msds (material safety sheet)

Phosphomycin Synthesis Reference

No information avaliable

Phosphomycin Molecular Weight

138.059 g/mol

Phosphomycin Melting Point

94 oC

Phosphomycin H2O Solubility

50 mg/mL (Sodium salt)

Phosphomycin State

Solid

Phosphomycin LogP

-0.912

Phosphomycin Dosage Forms

Powder

Phosphomycin Indication

For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.

Phosphomycin Pharmacology

Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.

Phosphomycin Absorption

Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to fosfomycin. Oral bioavailability under fasting conditions is 37%. When given with food, oral bioavailability is reduced to 30%

Phosphomycin side effects and Toxicity

LD50>5 g/kg (rats). Side effects may include diarrhea

Phosphomycin Patient Information

No information avaliable

Phosphomycin Organisms Affected

E. coli and other enteric bacteria