Phosphomycin
Phosphomycin Brand names, Phosphomycin Analogs
Phosphomycin Brand Names Mixture
- Micardis Plus (Hydrochlorothiazide + Telmisartan)
Phosphomycin Chemical_Formula
C3H7O4P
Phosphomycin RX_link
http://www.rxlist.com/cgi/generic2/fosfomycin.htm
Phosphomycin fda sheet
Phosphomycin msds (material safety sheet)
Phosphomycin Synthesis Reference
No information avaliable
Phosphomycin Molecular Weight
138.059 g/mol
Phosphomycin Melting Point
94 oC
Phosphomycin H2O Solubility
50 mg/mL (Sodium salt)
Phosphomycin State
Solid
Phosphomycin LogP
-0.912
Phosphomycin Dosage Forms
Powder
Phosphomycin Indication
For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.
Phosphomycin Pharmacology
Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.
Phosphomycin Absorption
Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to fosfomycin. Oral bioavailability under fasting conditions is 37%. When given with food, oral bioavailability is reduced to 30%
Phosphomycin side effects and Toxicity
LD50>5 g/kg (rats). Side effects may include diarrhea
Phosphomycin Patient Information
No information avaliable
Phosphomycin Organisms Affected
E. coli and other enteric bacteria
