Pectobloc

Pectobloc Brand names, Pectobloc Analogs

Pectobloc Brand Names Mixture

Viskazide 10/25tab (Hydrochlorothiazide + Pindolol)
Viskazide 10/50tab (Hydrochlorothiazide + Pindolol)

Pectobloc Chemical_Formula

C₁₄H₂₀N₂O₂

Pectobloc RX_link

http://www.rxlist.com/cgi/generic3/pindolol.htm

Pectobloc fda sheet

Pectobloc msds (material safety sheet)

Pectobloc MSDS

Pectobloc Synthesis Reference

No information avaliable

Pectobloc Molecular Weight

248.321 g/mol

Pectobloc Melting Point

167-171 ^oC

Pectobloc H₂O Solubility

7880 mg/L

Pectobloc State

Solid

Pectobloc LogP

2.525

Pectobloc Dosage Forms

Tablet

Pectobloc Indication

For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.

Pectobloc Pharmacology

Pindolol is a non-selective beta-adrenergic antagonist (beta-blocker) which possesses intrinsic sympathomimetic activity (ISA) in therapeutic dosage ranges but does not possess quinidine-like membrane stabilizing activity. Pindolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Pindolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Pindolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, pindolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.

Pectobloc Absorption

Rapidly and reproducibly absorbed (bioavailability greater than 95%).

Pectobloc side effects and Toxicity

LD₅₀=263 mg/kg (orally in rats). Signs of overdose include excessive bradycardia, cardiac failure, hypotension, and bronchospasm.

Pectobloc Patient Information

Pectobloc Organisms Affected

Humans and other mammals