Prinodolol en es it fr

Prinodolol Brand names, Prinodolol Analogs

Prinodolol Brand Names Mixture

  • Viskazide 10/25tab (Hydrochlorothiazide + Pindolol)
  • Viskazide 10/50tab (Hydrochlorothiazide + Pindolol)

Prinodolol Chemical_Formula

C14H20N2O2

Prinodolol RX_link

http://www.rxlist.com/cgi/generic3/pindolol.htm

Prinodolol fda sheet

Prinodolol msds (material safety sheet)

Prinodolol MSDS

Prinodolol Synthesis Reference

No information avaliable

Prinodolol Molecular Weight

248.321 g/mol

Prinodolol Melting Point

167-171 oC

Prinodolol H2O Solubility

7880 mg/L

Prinodolol State

Solid

Prinodolol LogP

2.525

Prinodolol Dosage Forms

Tablet

Prinodolol Indication

For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.

Prinodolol Pharmacology

Pindolol is a non-selective beta-adrenergic antagonist (beta-blocker) which possesses intrinsic sympathomimetic activity (ISA) in therapeutic dosage ranges but does not possess quinidine-like membrane stabilizing activity. Pindolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Pindolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Pindolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, pindolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.

Prinodolol Absorption

Rapidly and reproducibly absorbed (bioavailability greater than 95%).

Prinodolol side effects and Toxicity

LD50=263 mg/kg (orally in rats). Signs of overdose include excessive bradycardia, cardiac failure, hypotension, and bronchospasm.

Prinodolol Patient Information

Prinodolol Organisms Affected

Humans and other mammals