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Leptofen Brand names, Leptofen Analogs

Leptofen Brand Names Mixture

  • No information avaliable

Leptofen Chemical_Formula


Leptofen RX_link


Leptofen fda sheet

Leptofen msds (material safety sheet)

Leptofen MSDS

Leptofen Synthesis Reference

No information avaliable

Leptofen Molecular Weight

166.24 g/mol

Leptofen Melting Point

No information avaliable

Leptofen H2O Solubility

Appreciable as liquid hydrochloride salt

Leptofen State


Leptofen LogP


Leptofen Dosage Forms

Liquid for injection

Leptofen Indication

For the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises.

Leptofen Pharmacology

Edrophonium is a short and rapid-acting anticholinesterase drug. Its effect is manifest within 30 to 60 seconds after injection and lasts an average of 10 minutes. Edrophonium's pharmacologic action is due primarily to the inhibition or inactivation of acetylcholinesterase at sites of cholinergic transmission. Muscarinic receptors are found throughout the body, especially on muscle. Stimulation of these receptors causes to muscle contraction. In myasthenia gravis the body's immune system destroys many of the muscarinic receptors, so that the muscle becomes less responsive to nervous stimulation. Edrophonium chloride increases the amount of acetylcholine at the nerve endings. Increased levels of acetyl choline allow the remaining receptors to function more efficiently.

Leptofen Absorption

Rapidly absorbed.

Leptofen side effects and Toxicity

With drugs of this type, muscarine-like symptoms (nausea, vomiting, diarrhea, sweating, increased bronchial and salivary secretions and bradycardia) often appear with overdosage (cholinergic crisis).

Leptofen Patient Information

No information avaliable

Leptofen Organisms Affected

Humans and other mammals