Clobetasolpropionat mikron.
Clobetasolpropionat mikron. Brand names, Clobetasolpropionat mikron. Analogs
Clobetasolpropionat mikron. Brand Names Mixture
- No information avaliable
Clobetasolpropionat mikron. Chemical_Formula
C25H32ClFO5
Clobetasolpropionat mikron. RX_link
http://www.rxlist.com/cgi/generic/olux.htm
Clobetasolpropionat mikron. fda sheet
Clobetasolpropionat mikron. msds (material safety sheet)
Clobetasolpropionat mikron. Synthesis Reference
No information avaliable
Clobetasolpropionat mikron. Molecular Weight
466.97 g/mol
Clobetasolpropionat mikron. Melting Point
195.5-197 oC
Clobetasolpropionat mikron. H2O Solubility
3.86 mg/L
Clobetasolpropionat mikron. State
Solid
Clobetasolpropionat mikron. LogP
3.588
Clobetasolpropionat mikron. Dosage Forms
Foam (0.05%) and ointment (usp 0.05%, supplied in 15 g, 30 g, and 45 g tubes)
Clobetasolpropionat mikron. Indication
For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.
Clobetasolpropionat mikron. Pharmacology
Like other topical corticosteroids, clobetasol has anti-inflammatory, antipruritic, and vasoconstrictive properties. It is a very high potency topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.
Clobetasolpropionat mikron. Absorption
Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.
Clobetasolpropionat mikron. side effects and Toxicity
Oral LD50 in rat and mouse is >3000 mg/kg. Topically applied clobetasol can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).
Clobetasolpropionat mikron. Patient Information
Clobetasolpropionat mikron. Organisms Affected
Humans and other mammals
