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Cefalexin
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Cefalexin Brand names, Cefalexin Analogs

Cefalexin Brand Names Mixture

  • No information avaliable

Cefalexin Chemical_Formula

C16H17N3O4S

Cefalexin RX_link

http://www.rxlist.com/cgi/generic/cephalex.htm

Cefalexin fda sheet

Cefalexin FDA

Cefalexin msds (material safety sheet)

Cefalexin MSDS

Cefalexin Synthesis Reference

R. B. Morin, B. G. Jackson, U.S. Pat. 3,275,626,861 (1966,1970)

Cefalexin Molecular Weight

347.39 g/mol

Cefalexin Melting Point

326.8oC

Cefalexin H2O Solubility

1789 mg/L

Cefalexin State

Solid

Cefalexin LogP

0.019

Cefalexin Dosage Forms

Capsules (containing cephalexin monohydrate equivalent to 250 mg or 500 mg cephalexin); Tablet (containing cephalexin monohydrate equivalent to 250 mg or 500 mg of cephalexin); Suspension

Cefalexin Indication

For the treatment of respiratory tract infections caused by Streptococcus pneumoniae and Streptococcus pyogenes; otitis media due to Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Moraxella catarrhalis; skin and skin structure infections caused by Staphylococcus aureus and/or Streptococcus pyogenes; bone infections caused by Staphylococcus aureus and/or Proteus mirabilis; genitourinary tract infections, including acute prostatitis, caused by Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae.

Cefalexin Pharmacology

Cephalexin (also called Cefalexin) is a first generation cephalosporin antibiotic. It is one of the most widely prescribed antibiotics, often used for the treatment of superficial infections that result as complications of minor wounds or lacerations. It is effective against most gram-positive bacteria.

Cefalexin Absorption

Well absorbed from the gastrointestinal tract

Cefalexin side effects and Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting. The oral median lethal dose of cephalexin in rats is >5000 mg/kg.

Cefalexin Patient Information

Patients should be counseled that antibacterial drugs including Keflex should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Keflex is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Keflex or other antibacterial drugs in the future.

Cefalexin Organisms Affected

Enteric bacteria and other eubacteria