Keforal
Category
Keforal Brand names, Keforal Analogs
Keforal Brand Names Mixture
Keforal Chemical_Formula
C16H17N3O4S
Keforal RX_link
http://www.rxlist.com/cgi/generic/cephalex.htm
Keforal fda sheet
Keforal msds (material safety sheet)
Keforal Synthesis Reference
R. B. Morin, B. G. Jackson, U.S. Pat. 3,275,626,861 (1966,1970)
Keforal Molecular Weight
347.39 g/mol
Keforal Melting Point
326.8oC
Keforal H2O Solubility
1789 mg/L
Keforal State
Solid
Keforal LogP
0.019
Keforal Dosage Forms
Capsules (containing cephalexin monohydrate equivalent to 250 mg or 500 mg cephalexin); Tablet (containing cephalexin monohydrate equivalent to 250 mg or 500 mg of cephalexin); Suspension
Keforal Indication
For the treatment of respiratory tract infections caused by Streptococcus pneumoniae and Streptococcus pyogenes; otitis media due to Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Moraxella catarrhalis; skin and skin structure infections caused by Staphylococcus aureus and/or Streptococcus pyogenes; bone infections caused by Staphylococcus aureus and/or Proteus mirabilis; genitourinary tract infections, including acute prostatitis, caused by Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae.
Keforal Pharmacology
Cephalexin (also called Cefalexin) is a first generation cephalosporin antibiotic. It is one of the most widely prescribed antibiotics, often used for the treatment of superficial infections that result as complications of minor wounds or lacerations. It is effective against most gram-positive bacteria.
Keforal Absorption
Well absorbed from the gastrointestinal tract
Keforal side effects and Toxicity
Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting. The oral median lethal dose of cephalexin in rats is >5000 mg/kg.
Keforal Patient Information
Patients should be counseled that antibacterial drugs including Keflex should only be used to treat bacterial
infections. They do not treat viral infections (e.g., the common cold). When Keflex is prescribed to treat a
bacterial infection, patients should be told that although it is common to feel better early in the course of
therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of
therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria
will develop resistance and will not be treatable by Keflex or other antibacterial drugs in the future.
Keforal Organisms Affected
Enteric bacteria and other eubacteria
