Anchoic acid
Anchoic acid Brand names, Anchoic acid Analogs
Anchoic acid Brand Names Mixture
- No information avaliable
Anchoic acid Chemical_Formula
C9H16O4
Anchoic acid RX_link
http://www.rxlist.com/cgi/generic3/azelex.htm
Anchoic acid fda sheet
Anchoic acid msds (material safety sheet)
Anchoic acid Synthesis Reference
No information avaliable
Anchoic acid Molecular Weight
188.221 g/mol
Anchoic acid Melting Point
106.5 oC
Anchoic acid H2O Solubility
2400 mg/L (20°C)
Anchoic acid State
Solid
Anchoic acid LogP
1.646
Anchoic acid Dosage Forms
Cream (20%)
Anchoic acid Indication
For the topical treatment of mild-to-moderate inflammatory acne vulgaris.
Anchoic acid Pharmacology
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
Anchoic acid Absorption
Approximately 4% of the topically applied azelaic acid is systemically absorbed.
Anchoic acid side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg.
Anchoic acid Patient Information
Anchoic acid Organisms Affected
Various aerobic and anaerobic microorganisms
